Penn Medical Researchers Question the Value of an Increasingly Popular Breast Cancer Treatment

Contralateral prophylactic mastectomy (CRM) is a surgical procedure that removes the unaffected breast in patients with cancer in one breast. Younger women with breast cancer are often offered this procedure as a preventive measure. There has been a 150 percent increase in the number of CRM procedures in recent years.

But researchers at the Perelman School of Medicine at the University of Pennsylvania have found that CRM has only a slight benefit and produces only modest gains in life expectancy. Robert G. Prosnitz, as assistant professor of radiation oncology at Penn, stated, “We suspect that many of the women who elect to undergo CPM are acting on the belief the surgery will substantially reduce their overall risk of dying of breast cancer. However, our study shows that a woman’s risk of death from her primary breast cancer far outweighs her risk of death from a potential breast cancer developing in the unaffected breast. Additionally, the modest increase in life expectancy resulting from CPM may ultimately be negated by a reduction in quality of life.”

Dr. Prosnitz and his research team plan to develop and test decisions aids that will help patients decide if CRM or other alternative treatments are right for them.

1 COMMENT

  1. How is “a reduction in the quality of life” defined for a patient with one breast removed versus two? Personally my quality of life after double mastectomy is much improved not worrying about when breast cancer will turn up in my second breast. And, to prove my point, when the pathology came back on my “unaffected breast” there were signs of early DCIS! The peace of mind following double mastectomy totally outweighs the old fashioned notion that conserving one, non-matching breast, is worthwhile.

LEAVE A REPLY

Please enter your comment!
Please enter your name here

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Related Articles

Latest News

Jamie Hooyman to Lead North Central Missouri College

Most recently, Dr. Hooyman was vice president of academic affairs and provost of Northwest Missouri State University. She was the first woman to serve in that role.

Karen Davis O’Hara Named Director of Kenai Peninsula College in Alaska

Born and raised in Alaska, Dr. O'Hara previously spent more than two decades with the College of Education at California State University, Sacramento. More recently, she was executive director of Sierra College's Nevada County Campus.

Elizabeth Maher Muoio Is President of the Independent Colleges and Universities of New Jersey

The Independent Colleges and Universities of New Jersey is a nonprofit that supports New Jersey's 13 independent, nonprofit, public missions institutions of higher education through efforts such as philanthropy and public policy advocacy.

University of Texas at Arlington President Jennifer Cowley to Step Down

Four years after she was named the first woman president of the University of Texas at Arlington, Dr. Cowley has announced that she will step down and return to the faculty.

Megan Walsh to Lead Academic Affairs at Edgewood University in Wisconsin

Prior to her new role, Dr. Walsh was dean and campus director of the University of Maine at Machias. Before that, she spent more than a decade with St. Bonaventure University in New York.

Assistant Professor, Kenneth C. Griffin Department of Economics

The Kenneth C. Griffin Department of Economics at the University of Chicago invites applications for tenure-track faculty positions in Economics at the Assistant Professor level.

Tenure-Track or Tenured Assistant, Associate, and Full Professor, Department of Computer Science and Engineering

The Department of Computer Science and Engineering, College of Engineering at Texas A&M University, invites applications for ten full-time, tenure-track or tenure review upon hire, at all levels (Assistant, Associate, and Full Professor) with a nine-month academic appointment.

Tenure-Track Assistant Professor of Health Studies

We seek to make an appointment at the rank of Assistant Professor, in the health humanities or critical social sciences of health, including but not limited to medical anthropology and the history of medicine.

Tenure-Track Assistant Professor of Philosophy

Haverford College invites applications for a Tenure-Track Assistant Professor of Philosophy to begin Fall 2027. The Department of Philosophy seeks a full-time, tenure-track Assistant Professor beginning Fall semester, 2027.

Instructional Professor (Open Rank) in Global Studies

The Social Sciences Collegiate Division at the University of Chicago invites applications for an open-rank Instructional Professor position in the undergraduate Global Studies program.